- Trials with a EudraCT protocol (25)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
25 result(s) found for: Essential Gene.
Displaying page 1 of 2.
EudraCT Number: 2007-007335-99 | Sponsor Protocol Number: Tarceva-HH-2008 | Start Date*: 2009-08-24 | ||||||||||||||||
Sponsor Name:Herlev Hospital, Dept. of Haematology (L121) | ||||||||||||||||||
Full Title: A Phase II Study of Erlotinib in Patients with Polycythaemia Vera and Essential Thrombocythemia | ||||||||||||||||||
Medical condition: Polycythaemia Vera & Essential Thrombocythaemia | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DK (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-005306-49 | Sponsor Protocol Number: MK-0683-092 | Start Date*: 2008-09-03 | |||||||||||||||||||||
Sponsor Name:Department of Haematology, Herlev Hospital, University of Copenhagen | |||||||||||||||||||||||
Full Title: A Phase II Study of Vorinostat in Patients with Polycythaemia Vera and Essential Thrombocythaemia | |||||||||||||||||||||||
Medical condition: patients with polycythaemia vera or essential thrombocythaemia or myelofibrosis | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: DK (Completed) SE (Completed) NL (Completed) GB (Completed) | |||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2014-000972-24 | Sponsor Protocol Number: D3561C00004 | Start Date*: 2014-08-20 | |||||||||||
Sponsor Name:AstraZeneca AB | |||||||||||||
Full Title: A Randomized, Double blind, Placebo controlled, Multi center, Cross over Study of Rosuvastatin in Children and Adolescents (aged 6 to <18 years) with Homozygous Familial Hypercholesterolemia (HoFH) | |||||||||||||
Medical condition: Hypercholesterolemia - The current trial will study children with Homozygous Familial Hypercholesterolemia (HoFH) | |||||||||||||
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Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: SE (Completed) NL (Completed) BE (Completed) DK (Completed) DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-004746-99 | Sponsor Protocol Number: D356NC00001 | Start Date*: 2015-02-23 |
Sponsor Name:AstraZeneca AB | ||
Full Title: An Open-Label Long-Term Extension to the Randomized, Double-blind, Placebo-controlled, Multi-center, Cross-over Study of Rosuvastatin in Children and Adolescents (aged 6 to <18 years) with Homozygo... | ||
Medical condition: Hypercholesterolemia - The current trial will study children with Homozygous Familial Hypercholesterolemia (HoFH). | ||
Disease: | ||
Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | |
Trial protocol: BE (Completed) SE (Prematurely Ended) DK (Completed) | ||
Trial results: View results |
EudraCT Number: 2013-005466-19 | Sponsor Protocol Number: R0002198 | Start Date*: 2014-05-26 |
Sponsor Name:RadboudUMC | ||
Full Title: Cytokine inhibition in Chronic Fatigue Syndrome patients - a pilot study. | ||
Medical condition: Chronic Fatigue Syndrome | ||
Disease: | ||
Population Age: Adults | Gender: Female | |
Trial protocol: NL (Completed) | ||
Trial results: (No results available) |
EudraCT Number: 2012-003276-39 | Sponsor Protocol Number: 09072012 | Start Date*: 2013-01-09 | ||||||||||||||||
Sponsor Name:Hæmatologisk afdeling, Roskilde Sygehus, Region Sjælland | ||||||||||||||||||
Full Title: Investigation of the value of Iron and Bonemarrow stimulation in differential diagnostic of Polycythemia Vera and Essential Thrombocytosis | ||||||||||||||||||
Medical condition: Polycythemia Vera Essential thrombocytosis | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DK (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-017349-77 | Sponsor Protocol Number: TIGET-MLD | Start Date*: 2010-03-15 | |||||||||||
Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR | |||||||||||||
Full Title: A Phase I/II clinical trial of hematopoietic stem cell gene therapy for the treatment of Metachromatic Leukodystrophy | |||||||||||||
Medical condition: metachromatic leukodystrophy | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-002042-32 | Sponsor Protocol Number: CPX-351-TA-SMP | Start Date*: 2021-09-16 | |||||||||||
Sponsor Name:FILO | |||||||||||||
Full Title: A phase II study of CPX-351 monotherapy in Acute Myeloid Leukemia secondary to Myeloproliferative neoplams | |||||||||||||
Medical condition: newly secondary AML according to WHO 2016 classification following an antecedent of Myeloproliferative Neoplasm including Essential Thrombocythemia (ET), Polycythemia Vera (PV), primary or secondar... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-000784-33 | Sponsor Protocol Number: TacTremorConversion | Start Date*: 2017-07-31 | |||||||||||
Sponsor Name:Fundació Clínic per a la Recerca Biomèdica | |||||||||||||
Full Title: Effect of Envarsus conversion on tacrolimus-associated tremor in renal transplant patients. An open-label, single centre, prospective pharmacodynamic/pharmacokinetic clinical study | |||||||||||||
Medical condition: Tacrolimus-associated tremor | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-002857-41 | Sponsor Protocol Number: BORTEJECT | Start Date*: 2013-07-11 |
Sponsor Name:Universitätsklinik für Innere Medizin III, Medizinische Universität Wien | ||
Full Title: Bortezomib in late antibody-mediated kidney transplant rejection (BORTEJECT Study) | ||
Medical condition: Late antibody-mediated kidney allograft rejection | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: AT (Completed) | ||
Trial results: View results |
EudraCT Number: 2019-004583-22 | Sponsor Protocol Number: IDRLS | Start Date*: 2021-06-13 |
Sponsor Name:Medical University of Innsbruck | ||
Full Title: Prospective analysis of the therapeutic efficacy of iron isomaltoside in combination with or without dopaminergic therapy in patients with restless legs syndrome | ||
Medical condition: Restless leg syndorme | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: AT (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2011-000261-12 | Sponsor Protocol Number: CNTO328MDS2001 | Start Date*: 2011-09-28 | ||||||||||||||||
Sponsor Name:Janssen-Cilag International N.V. | ||||||||||||||||||
Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Subjects with International ... | ||||||||||||||||||
Medical condition: Anemia associated with Low- or Intermediate-1-Risk Myelodysplastic Syndrome | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: BE (Completed) ES (Prematurely Ended) SE (Completed) NL (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2020-000111-69 | Sponsor Protocol Number: PAC303 | Start Date*: 2020-08-04 | |||||||||||||||||||||
Sponsor Name:CTI BioPharma Corp. | |||||||||||||||||||||||
Full Title: PACIFICA Phase 3: A Randomized, Controlled Phase 3 Study of Pacritinib Versus Physician’s Choice in Patients with Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post Essential Thro... | |||||||||||||||||||||||
Medical condition: Primary Myelofibrosis, Post-essential thrombocythemia myelofibrosis with Severe Thrombocytopenia (Platelet Counts <50,000/μL), Post polycythaemia vera myelofibrosis | |||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||
Trial protocol: CZ (Ongoing) HU (Ongoing) ES (Ongoing) FR (Ongoing) BG (Ongoing) IT (Ongoing) | |||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2018-002915-93 | Sponsor Protocol Number: ACE-536-LTFU-001 | Start Date*: 2019-06-26 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Celgene Corporation | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: A phase 3B, open-label, single-arm, rollover study to evaluate long-term safety in subjects who have participated in other Luspatercept (ACE-536) clinical trials. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: Prior participation on a clinical trial of luspatercept (ACE-536) in protocols eligible for participation in this study ACE-536-LTFU-001 with the following medical conditions: - myelodysplastic syn... | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: DE (Trial now transitioned) SE (Trial now transitioned) NL (Trial now transitioned) GB (GB - no longer in EU/EEA) FR (Ongoing) GR (Trial now transitioned) ES (Ongoing) BE (Ongoing) BG (Ongoing) IT (Ongoing) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2014-000411-14 | Sponsor Protocol Number: 6639 | Start Date*: 2014-07-17 | |||||||||||
Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust | |||||||||||||
Full Title: A randomised double blind dose non-inferiority trial of a daily dose of 600mg versus 300mg versus 100mg of enteric coated aspirin as a cancer preventive in carriers of a germline pathological misma... | |||||||||||||
Medical condition: Lynch Syndrome also known as HNPCC (non hereditary non polyposis colorectal cancer). | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) FI (Ongoing) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2010-019577-16 | Sponsor Protocol Number: EGF114299 | Start Date*: 2010-12-21 | |||||||||||
Sponsor Name:Novartis Pharma Services AG | |||||||||||||
Full Title: A Phase III trial to compare the safety and efficacy of lapatinib plus trastuzumab plus an aromatase inhibitor (AI) versus trastuzumab plus an AI versus lapatinib plus an AI as first- or second-lin... | |||||||||||||
Medical condition: HER2-positive metastatic breast cancer who have received prior trastuzumab and endocrine therapies | |||||||||||||
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Population Age: Adults, Elderly | Gender: Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) HU (Completed) IE (Prematurely Ended) PL (Completed) BE (Completed) BG (Prematurely Ended) NO (Ongoing) GB (Completed) LT (Prematurely Ended) PT (Prematurely Ended) ES (Ongoing) GR (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2011-003633-33 | Sponsor Protocol Number: MAXEPA01 | Start Date*: 2011-09-29 | |||||||||||
Sponsor Name:Central Manchester University Hospitals NHS Foundation Trust | |||||||||||||
Full Title: The effect of purified fish oils on glucose regulation in Congenital Hyperinsulinism of Infancy (CHI) | |||||||||||||
Medical condition: Congenital hyperinsulinism | |||||||||||||
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Population Age: Infants and toddlers, Children, Under 18 | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2013-001664-34 | Sponsor Protocol Number: 12028-FC-SS | Start Date*: 2013-08-30 | |||||||||||
Sponsor Name:Belfast HSC Trust [...] | |||||||||||||
Full Title: Vit-D in CRC - A Randomised Double Blind Placebo-Controlled Clinical Trial Of a Single Oral Cholecalciferol Treatment Against Surrogate End Point Biomarkers (SEBs) In Colon Cancer (CRC) Patients | |||||||||||||
Medical condition: Colon cancer | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2021-003417-19 | Sponsor Protocol Number: BN42644 | Start Date*: 2022-01-03 | ||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:F. HOFFMANN - LA ROCHE LTD. | ||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: A TWO-PART, SEAMLESS, MULTI-CENTER, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND EFFICACY OF RO7204239 IN COMBI... | ||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: Spinal Muscular Atrophy (SMA) | ||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Children, Under 18 | Gender: Male, Female | |||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: IT (Ongoing) PL (Ongoing) DE (Ongoing) BE (Ongoing) NL (Ongoing) ES (Ongoing) PT (Ongoing) | ||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2012-002933-12 | Sponsor Protocol Number: 11/0090 | Start Date*: 2014-04-07 | |||||||||||
Sponsor Name:University College London, | |||||||||||||
Full Title: A Phase II pilot study to explore treatment with Sodium Valproate in Adults with McArdle Disease (Glycogen Storage Disorder Type V, GSDV) | |||||||||||||
Medical condition: McArdle disease (Glycogen storage disease type V, GSDV). The condition is an inherited disorder of skeletal muscle that causes exercise intolerance. The condition can give way to potential rhabdom... | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Completed) | |||||||||||||
Trial results: View results |
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